Bound Volume Number
Volume VIII
Degree Type
Honors Capstone Project
Date of Submission
Spring 5-2016
Capstone Advisor
Jeremy Gilbert
Capstone Major
Biomedical and Chemical Engineering
Capstone College
Engineering and Computer Science
Audio/Visual Component
no
Keywords
lectrochemical tests on retrieved inflamed joint fluids
Capstone Prize Winner
no
Won Capstone Funding
no
Honors Categories
Sciences and Engineering
Subject Categories
Biomedical Engineering and Bioengineering | Chemical Engineering
Abstract
There is currently no systematic way to analyze the corrosion response of orthopedic alloys in contact with human joint fluid. The goal of this project was to design and test a small device that can successfully run electrochemical tests on retrieved inflamed joint fluids. Methods of fluid testing analysis were also explored. The a small electrochemical cell was created using polypropylene for the body and an electrode cartridge that could be disposed of after each test. In total the device could hold 4 mL of liquid. Testes were preformed using titanium, stainless steel, and CoCrMo alloys as the working electrodes and were tested in solutions of PBS and AMEM (10% fetal bovine serum) and additions of 0.1 mM of FeCl3 and H2O2 (5, 10, 25 mM) to simulate the inflamed joint fluid created by the oxidative burst reaction. Three electrochemical tests were run to evaluate the cell and included open circuit potential, impedance, and anodic polarization. The results of these tests indicated that the device can be used to analyze the corrosion response of metallic alloys in joint fluid, and that the additions of FeCl3 and H2O2 increased potential of these alloys to corrode.
Recommended Citation
Pieri, Kathleen, "Development of an Inflammatory Joint Fluid Corrosion Assessment Method for Metallic Biomaterials" (2016). Renée Crown University Honors Thesis Projects - All. 960.
https://surface.syr.edu/honors_capstone/960
Creative Commons License
This work is licensed under a Creative Commons Attribution 3.0 License.
