Document Type
Article
Date
2008
Keywords
Caenorhabditis elegans, RNA, functional genomics, gene networks, gene interaction
Language
English
Disciplines
Biology
Description/Abstract
The RNA interference (RNAi) method for targeted gene silencing is widely used in Caenorhabditis elegans for large-scale functional genomic studies, analysis of limited gene sets and detailed analysis of individual gene function. The application of RNAi has identified genes that participate in various aspects of development, physiology and cell biology. In addition, RNAi has been used to identify interacting genes and to study functionally redundant genes. This review discusses the various applications of RNAi in C. elegans, focusing particularly on the analysis of developmental processes.
Recommended Citation
Maine, Eleanor M., "Studying gene function in Caenorhabditis elegans using RNA-mediated interference" (2008). Biology - All Scholarship. 18.
https://surface.syr.edu/bio/18
Source
Oxford Journals
Creative Commons License
This work is licensed under a Creative Commons Attribution 3.0 License.
