Document Type

Article

Date

2008

Embargo Period

9-29-2010

Keywords

Caenorhabditis elegans, RNA, functional genomics, gene networks, gene interaction

Language

English

Disciplines

Biology

Description/Abstract

The RNA interference (RNAi) method for targeted gene silencing is widely used in Caenorhabditis elegans for large-scale functional genomic studies, analysis of limited gene sets and detailed analysis of individual gene function. The application of RNAi has identified genes that participate in various aspects of development, physiology and cell biology. In addition, RNAi has been used to identify interacting genes and to study functionally redundant genes. This review discusses the various applications of RNAi in C. elegans, focusing particularly on the analysis of developmental processes.

Source

Oxford Journals

Creative Commons License

Creative Commons License
This work is licensed under a Creative Commons Attribution 3.0 License.

Included in

Biology Commons

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