Date of Award
Master of Science (MS)
James T. Spencer
John W. Tillotson
imprinted, MIP, molecularly, polymer, sensor, specificity
Physical Sciences and Mathematics
Molecularly imprinted polymers (MIPs) have numerous practical applications, including integration with quartz crystal microbalances to make specific, stable, chemical sensors, but most published research literature does not provide details concerning the specificity or stability of such an imprinted polymer. A polymer made from polyacrylic acid monomers, templated with benzoic acid, was tested for specificity with solutions of benzoic acid, acetic acid, phenol, and terephthalic acid passed through samples of uniform size under vacuum filtration. Additionally, MIP samples were also stored for extended periods of time in varied microclimates and then tested for performance, and consequently, stability. Initial conclusions indicate that a benzoic acid-templated MIP can capture the specific targets of benzoic acid, benzaldehyde, and terephthalic acid, while excluding species of similar size and functionality. Furthermore, benzoic acid-templated MIPs operate best when stored in a dry environment between 9ºC and far below 120ºC with shelf-lives for at least months.
Shepherd, Stephen Robert, "EXPLORING SPECIFICITY AND STABILITY OF A MOLECULARLY IMPRINTED POLYMER" (2018). Theses - ALL. 289.