Synthesis and Structural Characterization of Mn(II) and Co(II) Pyrophosphate Complexes with 1,10-phenanthroline-5,6-dione
Date of Award
December 2017
Degree Type
Thesis
Degree Name
Master of Science (MS)
Department
Chemistry
Advisor(s)
Robert P. Doyle
Second Advisor
Jon A. Zubieta
Keywords
biology, Cobalt, magnetics, Manganese, Mycobacterium tuberculosis, phendione
Subject Categories
Physical Sciences and Mathematics
Abstract
The overall goal of this research is to synthesize and characterize new Mn(II) and Co(II) complexes with phendione as a terminal ligand and pyrophosphate as a capping or bridging ligand. We would like to produce Mn(II) and Co(II) compounds that: 1) are aqueously soluble to test for activity against Mycobacterium tuberculosis (M. tb); 2); contain multinuclear metal centers to test for magnetic properties and 3) offer open coordination sites to test for their catalytic activity in ketone oxidations. Chapter 2 focuses on the synthesis and characterization of Mn(II) complexes with phendione and their activity against M. tb as well magnetic properties of one Mn(II) complex. Two Co(II) complexes with phendione were synthesized, characterized and tested for magnetic susceptibility, described in Chapter 3. The synthesis and characterization of new Mn(II) and Co(II) complexes with phendione allow us to gain insight on the effect of the phendione ligand on targeting M. tb, the electronics of magnetic systems, and catalytic activity of the coordination complexes discussed in Chapter 7.
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Recommended Citation
Zito, Elaina, "Synthesis and Structural Characterization of Mn(II) and Co(II) Pyrophosphate Complexes with 1,10-phenanthroline-5,6-dione" (2017). Theses - ALL. 179.
https://surface.syr.edu/thesis/179
