Document Type

Honors Capstone Project

Date of Submission

Spring 5-1-2009

Capstone Advisor

Dr. R. Craig Albertson

Honors Reader

Dr. Al Uy

Capstone Major

Biology

Capstone College

Arts and Science

Audio/Visual Component

no

Capstone Prize Winner

no

Won Capstone Funding

yes

Honors Categories

Sciences and Engineering

Subject Categories

Biology

Abstract

To understand the evolution of craniofacial asymmetry within the Perissodini tribe, a group of scale-eating fish found in Lake Tanganyika, we performed shape analysis on their craniofacial architecture, and applied a simple lever model to measure asymmetry in lower-jaw mechanics. We found that craniofacial asymmetries were the consequence of sided differences in size and shape of craniofacial elements, and that sided differences in shape predict the lateralization of force and speed of the lower jaw in derived species. Quantitative Trait Locus analysis in Lake Malawi cichlids identified a single locus of major effect for jaw laterality, the first genetic marker for handedness in an antisymmetric trait. Studying the evolution of laterality in Perissodus and ultimately identifying the genetic factors that contribute to the asymmetric development of skeletal structures will shed light on the evolutionary and clinical consequences of vertebrate laterality.

Creative Commons License

Creative Commons Attribution-Noncommercial-No Derivative Works 3.0 License
This work is licensed under a Creative Commons Attribution-Noncommercial-No Derivative Works 3.0 License.

Included in

Biology Commons

Share

COinS
 
 

To view the content in your browser, please download Adobe Reader or, alternately,
you may Download the file to your hard drive.

NOTE: The latest versions of Adobe Reader do not support viewing PDF files within Firefox on Mac OS and if you are using a modern (Intel) Mac, there is no official plugin for viewing PDF files within the browser window.