Document Type

Honors Capstone Project

Date of Submission

Spring 5-1-2011

Capstone Advisor

Mark Glauser

Honors Reader

John Dannenhoffer

Capstone Major

Mechanical and Aerospace Engineering

Capstone College

Engineering and Computer Science

Audio/Visual Component

no

Capstone Prize Winner

no

Won Capstone Funding

yes

Honors Categories

Sciences and Engineering

Subject Categories

Aerospace Engineering | Other Aerospace Engineering

Abstract

Cerebral aneurysms affect 5% of western populations and can cause morbidity and mortality if they rupture. Various treatments can be used to minimize the risk of rupture, with new diagnostics and treatments under development that require information from non-invasive techniques such as Particle Imaging Velocimetery (PIV). The current study focused on developing a setup as a basis for future experiments and work on intracranial aneurysms involving PIV. PIV experimentation and data collection were carried out during the summer of 2010 at Ohta Labs of Tohoku University in Sendai, Japan. The experimental setup consisted of a pulsatile flow system, which was configured to realistically reproduce conditions found in cerebral aneurysms. PIV is often used as a validation measure in tandem with Computational Fluid Dynamic (CFD) research, and it is important that experimental setups in PIV produce realistic hemodynamics. A PIV system was used to record velocity field data in select planes through a silicone model of a curved artery with a saccular aneurysm attached at a 90 degree angle to the bend. Hemodynamics throughout the aneurysm and near aneurysm region of the parent artery were successfully recorded for future reference with CFD. Focal attributes to confirm experimental success were: 1) creation of laminar flow before the aneurysm; 2) development of Dean Vortices that interacted predictably with the aneurysm; and 3) aneurysmal inflow consistent with physiological data.

Creative Commons License

Creative Commons Attribution-Noncommercial-No Derivative Works 3.0 License
This work is licensed under a Creative Commons Attribution-Noncommercial-No Derivative Works 3.0 License.

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