Title
RNAi As a Tool for Understanding Germline Development in Caenorhabditis elegans: Uses and Cautions
Document Type
Article
Date
2001
Keywords
Caenorhabditis elegans, C. elegans, RNA interference, RNAi, germ line, germ cells, development, germline development.
Language
English
Disciplines
Biology
Description/Abstract
RNA-mediated genetic interference (RNAi) has become a very useful tool for analyzing gene function in development and other processes. RNAi can be used as a complement to traditional genetic studies or as a primary means of determining biological function. However, the efficacy of RNAi depends on a variety of factors that the researcher must take into consideration. This review focuses on germline development in the nematode, Caenorhabditis elegans, and discusses the uses and limitations of RNAi in providing new information about gene function as well as the possible endogenous role RNAi plays in germline physiology.
Recommended Citation
Maine, Eleanor M., "RNAi As a Tool for Understanding Germline Development in Caenorhabditis elegans: Uses and Cautions" (2001). Biology - All Scholarship. 11.
https://surface.syr.edu/bio/11
Source
Local input
Creative Commons License
This work is licensed under a Creative Commons Attribution 3.0 License.
