The Reaction of 1-Alkyl-3-Substituted Pyridinium Salts with Alkaline Hydrogen Peroxide
Date of Award
Doctor of Philosophy (PhD)
Enzymic oxidation reactions, Coenzyme, Dihydronicotinamide adenine dinucleotide
Many important enzymic oxidation reactions which combine various substrates with oxygen in living systems require the presence of the coenzyme, dihydronicotinamide adenine dinucleotide (NADH). A few examples of such oxidations are aerobic respiration, hydroxylation of aromatic rings, lactonization of ketones, and epoxidation of squalene in the biosynthesis of steroids. The coenzyme is utilized as a source of electrons in these reactions but its precise role has not always been determined.
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Bristol, Douglas Walter, "The Reaction of 1-Alkyl-3-Substituted Pyridinium Salts with Alkaline Hydrogen Peroxide" (1969). Chemistry - Dissertations. 148.