Document Type

Article

Date

2001

Embargo Period

9-29-2010

Keywords

Caenorhabditis elegans, C. elegans, RNA interference, RNAi, germ line, germ cells, development, germline development.

Language

English

Disciplines

Biology

Description/Abstract

RNA-mediated genetic interference (RNAi) has become a very useful tool for analyzing gene function in development and other processes. RNAi can be used as a complement to traditional genetic studies or as a primary means of determining biological function. However, the efficacy of RNAi depends on a variety of factors that the researcher must take into consideration. This review focuses on germline development in the nematode, Caenorhabditis elegans, and discusses the uses and limitations of RNAi in providing new information about gene function as well as the possible endogenous role RNAi plays in germline physiology.

Source

Local input

Creative Commons License


This work is licensed under a Creative Commons Attribution 3.0 License.

Included in

Biology Commons

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